The post-synaptic side of the synapse is now recognized as a site of highly dynamic membrane trafficking events, where some neurotransmitter receptors shuttle between the plasma membrane and ...
The three best examples of ion channel/receptor clustering in the nervous system are found at the synapse, the node of Ranvier, and the axon initial segment (AIS). In the case of the synapse, the ...
both LTP and LTD can occur at the same synapse in response to different patterns of activation of NMDA (N-methyl-D-aspartate) receptors. This raises the question of whether specific mechanisms ...
is seriously affected when either of these kainate receptors is suppressed, both being necessary for synapse formation. Ana Valero Paternain, the co-first author of the study, explains ...
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR ... dynamics at the immune synapse – where CAR T cells bind ...
A study shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators examined how molecular dynamics at the immune synapse ...
(1) A chimeric antigen receptor (CAR) is a modular, synthetic receptor that endows T cells with different ... that bind peptides and engage with the CD3ε subunit of the endogenous TCR to create a ...
A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells ...
Leukocytes are particularly well suited for these tasks because they can completely reorganize their structure in a matter of minutes in response to surface receptor stimulation ... known as a ...
10, 2025) – A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR ... at the immune synapse – where CAR T cells ...