Using this technique, the relative mRNA levels of genes showing cell type–specific expression can be accurately determined even in tissue samples containing a heterogeneous blend of cells of ...

Despite these structural features, mRNA molecules are relatively unstable compared to DNA ... The ability to harness the power of mRNA to modulate gene expression and produce desired proteins holds ...

From being a promising yet underexplored approach in the 1990s, mRNA therapeutics have evolved dramatically. The discovery of ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA). This process takes place in the nucleus and occurs in a series of stages. The two ...

Molecular biologists refer to mRNA as a one-stranded molecule ... identities by adopting particular gene expression profiles but understanding the relative contributions of mRNA transcription ...

and localization of the mRNA. Alternative polyadenylation is a mechanism of regulation of gene expression that is widespread, but often overlooked since it is relatively difficult to study.” ...