W orking with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different ...

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The ...

The retina is a complex structure in the eye that plays a crucial role in visual processing. It contains various types of cells, including photoreceptors, bipolar cells, and ganglion cells ...

The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the ...

The results are consistent with the notion that a primitive retina (similar to that of hagfish) contained ciliary photoreceptors connected directly to projection neurons, and that subsequently ...

A multidisciplinary team of researchers from the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) and ...

A new study reveals the potential of two compounds in treating retinitis pigmentosa, a blinding genetic disorder. These compounds, identified through virtual screening, have shown promising results in ...

Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.

The retinal toxicity service assesses the impact of novel substances on cell viability after photoreceptor degeneration. Newcells also compares multiple differentiation time points. This quick ...

Based on in situ hybridization and hypothyroid studies, thyroid hormone appears to target photoreceptor development. The hormone may be acting in at least two ways. It could instruct neuronal ...

Models Retinal organoids with photoreceptors (cone and rod), retinal ganglion cells, horizontal cells, and amacrine cells (derived from healthy (WT) or gene-edited patient-specific iPSCs provided ...

Two compounds prolonged the survival of photoreceptors in a retinitis pigmentosa mouse model for rod opsin misfolding ...