随着年龄的增长，体内的细胞逐渐进入衰老状态，这些衰老细胞（senescent ...

Senescent cells have both harmful roles ... characterized by increased Senescence-Associated β-Galactosidase (SA-β-Gal) staining and reduced Ki67 expression. Additionally, p16-tdT cells ...

A handful of clinical trials are underway to find out whether drugs that target senescent cells can slow the ravages of old age. After a year teaching an algorithm to differentiate between the ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Traditional methods for detecting senescent cells, such as β-galactosidase staining and immunohistochemistry, have limitations in terms of specificity and sensitivity. The introduction of ...

In the course of their study, the researchers found that diseases associated with aging and obesity are triggered and progress when senescent cells accumulate in internal organs, blood vessels and ...