Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood disease, were more likely to survive malaria, a disease which kills some 1.2 million people every year.

Can we predict that natural selection will weed out genetic disease over time? Sickle-cell trait haplotype distribution shows the genetic advantages of this mutation. In the deoxygenated ...

On this map, the distribution of sickle-cell anemia haplotypes among nations with high prevalence of the disease are shown. Five distinct beta-globin haplotypes (indicated by colors) are found in ...

A groundbreaking study reveals that individuals with sickle cell disease show premature brain aging, appearing 14 years older ...

A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual ...

Since two gene therapies were approved for sickle cell disease in late 2023, only a handful of patients have started the ...

Individuals with sickle cell disease – a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen ...

Sickle cells grow into crescent shapes, instead of the round red blood cells seen in people without the gene New research suggests that the history of sickle-cell disease goes back to a mutation ...

In 2007, teams from UAB and the Massachusetts Institute of Technology reported the first successful treatment of sickle cell anemia in experimental animals using induced pluripotent stem (iPS) cells.

Jimi Olaghere thought he would have to wait decades to be freed from his sickle cell disease - but now scientists have engineered his blood to overcome the disease which left him in constant pain.

In The Pitt Season 1 Episode 2, sickle cell disease (SCD) is the main focus, as it brings to light the tough medical and racial challenges that people with this illness have to face every day.