What was puzzling was why sickle cell anemia was so prevalent in some African populations. How could a "bad" gene-- the mutation that causes the sometimes lethal sickle cell disease -- also be ...

Because the sickle-cell mutation is present only on the β-globin ... and sickle-shaped red blood corpuscles in a case of severe anemia. Archives of Internal Medicine 6, 517–521 (1910) Ingram ...

Jan. 17, 2025 — A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a ...

Many individuals with sickle cell anemia undergoing controlled ovarian ... cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred ...

It is a potential game changer for young sickle cell patients because the therapy eliminates the need for a suitable donor and removes the mutation for a life free of sickle cell disease." ...

Stem cell transplant in young adults and adolescents with severe sickle cell disease may be a feasible option, according to a ...

The sister of a"caring and selfless” dad whose life was tragically cut short of Christmas Day after a long battle with sickle cell anemia has ... arises from a genetic mutation affecting ...

IMMvention Therapeutix, Inc., a Durham early-stage biotechnology company focused on discovering and developing human ...

New data from a Phase 1b clinical trial testing Fulcrum's pociredir for sickle cell disease are expected by the middle and ...

If a mutation occurs in a gene that results in ... in their body cells then they will have the genetic condition sickle cell anaemia. The sickle shaped red blood cells can block blood vessels ...