Mapping the key signaling molecules in biochemical pathways will be central to future drug discovery efforts. Signal transduction describes the process of conversion of external signals ...

4). Because signal transduction pathways represent the nexus through which nearly all biological information moves between and within cells and across organisms, manipulating these pathways is ...

Davis, University of Massachusetts Medical School, Howard Hughes Medical Institute. The signal transduction pathways of mitogen-activated protein (MAP) kinases have been actively studied for some time ...

DIRECT EFFECTS: Steven Hebert, left, and Edward Brown and colleagues found that Ca 2+ receptors influence signal transduction. "Although the importance of intracellular Ca2+ ions in signal ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

Members of the program engage in research aimed at obtaining a mechanistic understanding of signal transduction and cellular regulation, which includes cellular signaling pathways and downstream ...