For example, if the outgoing interaction strengths of one sender are spread evenly across all receivers ... which were sent by B cells and received by B cells; significant downregulation of ...
First, generate known ligand-receptor pairs from CellChatDB, then select short-range and long-range interactions from known pairs for each dataset (top left). Next, perform spatial cell type ...
Armingol, E., Officer, A., Harismendy, O. & Lewis, N.E. Deciphering cell-cell interactions and communication from gene expression. Nat Rev Genet 22, 71–88 (2021 ...
spleen and peyer’s patch required ligand-receptor engagement between lymphotoxin (LT) LTα1β2 produced by immune cells and LTβ receptor (LTβR) expressed on various stromal fibroblast subsets.
Background: We conducted an investigation into the characteristics of single-cell differentiation data in gliomas ... and the CellChatDB.human database for ligand-receptor interactions. Signaling ...
Identifying hitherto unknown networks of biochemical signaling pathways will propel the field of single-particle live cell and quantitative microscopy ... of freely-diffusing homodimers of the ...
SMFS allows the direct measurement of the strength and kinetics of receptor-ligand interactions at the single-molecule level. By attaching a receptor to a surface ... such as antibody-antigen ...
Background Rheumatoid (RA) and psoriatic arthritis (PsA) are common autoimmune and autoinflammatory diseases of unknown aetiology characterised by complex synovial pathology with a detrimental effect ...