EurekAlert!1mon
Combining long- and short-read sequencing in single cells reveals new mRNAs in neurodegenerative diseases
“However, typical single-cell sequencing experiments use what ... so to better capture these, we also used long-read sequencing that reads between 5,000 and 30,000 base pairs at a time and ...
technologynetworks6d
Long Read Sequencing Speeds Up Rare Disease Diagnosis
UC Santa Cruz researchers showcase how long-read sequencing can diagnose rare genetic diseases in days instead of years.
Long read sequencing reveals more genetic information while cutting time and cost of rare disease diagnoses
One in every 10 people worldwide is impacted by a rare genetic disease but about 50% of them remain undiagnosed despite rapid ...
GEN6d
Long-Read Nanopore Sequencing Improves Rare Disease Diagnosis
Long read sequencing revealed more genetic information in cases of 42 patients with rare diseases while cutting time and cost of diagnoses.
BioTechniques3y
Next-generation sequencing: in summary
However, the latest next-generation sequencing techniques are able to produce longer reads from much larger fragments of DNA nucleotide strands. There are two well-established processes for the ...
Brazilian researchers create cell atlas for brain malformation associated with severe epilepsy
Using a single-cell sequencing technique, it was possible to characterize the different cell types present in the brain ...
Complex engineering of human cell lines reveals genome's unexpected resilience to structural changes
The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more ...
GEN2d
Generative AI Model, ChromoGen, Rapidly Predicts Single-Cell Chromatin Conformations
New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.