Single-stranded RNA molecule (usually from 21 to 25 nucleotides in length) produced by the cleavage and processing of double-stranded RNA; binds to complementary sequences in mRNA and brings about ...
They observed that introducing double-stranded RNA (dsRNA) into the worm led to the silencing of genes with complementary ... it is possible to develop highly specific and effective treatments with ...
and these authors have now shown that intravenous injection of antiviral small interfering RNA (siRNA) bound to a short virus-derived peptide offers protection against fatal viral encephalitis in ...
Both microRNAs and the related class of small interfering RNAs (siRNAs) are small snippets of RNA—just 21 or 22 nucleotides long—that bind to specific messenger RNAs (mRNAs) and repress them.
This can lead to the accumulation of the drug and severe toxicity, causing symptoms such as neutropenia, mucositis, and neurotoxicity. RNA-based therapies, such as small interfering RNA (siRNA) and ...