For example, C/D and H/ACA RNP function seems to require the adjustment of the conformation of the guide RNA by the binding of the auxiliary protein L7Ae. The study of small nuclear ...

As small RNA populations from different species throughout ... The duplex is paired such that each 3′ end contains a 2-nucleotide overhang. NLS, nuclear localization signal.

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

It can also create a few other types of RNA, including small nuclear RNA (which forms complexes with other proteins to process mRNA) and microRNA (which regulates the translation process). An RNA ...

In the 3’ to 5’ pathway, RNA degradation is catalyzed by a multi-subunit 3’ to 5’ exoribonuclease complex, the RNA exosome. The exosome also participates in processing small nucleolar and small ...

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published ...

Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...

This dramatically accelerates the development of RNA editing therapeutics for a wide range of genetic disorders." The second ...

Y-Box binding protein 3 (YBX3) and splicing factor 3b subunit 6 (SF3B6) were confirmed to be upregulated in RA-FLS and CIA mice, while eukaryotic translation initiation factor 4A1 (EIF4A1) and U2 ...