衰老是生命中不可避免的过程，但其背后的生物学机制却一直是科学界探讨的焦点。多年来，研究人员一直试图揭示为何随着时间推移，我们的身体会经历功能衰退和疾病的增加。在此背景下，DNA甲基化（DNA ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells ...

A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views ...

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old ...

Researchers uncover a link between genetic mutations and epigenetic changes, two major contributors to aging. Their findings ...

Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

New research shows persistent DNA lesions in stem cells contribute to mutations, with links to blood cancers and external ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

Quotient Therapeutics, a biotech company founded in 2022, hopes to take this transatlantic model and commercialise it. Its main research lab is in Great Chesterford, a village just outside Cambridge, ...