Mayo Clinic researchers find that stem cells with the highest Myc expression become dominant in driving lung remodeling .

Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...

Discovering genes and microRNAs involved in human lung development unveils IGFBP3/miR-34a dynamics and their relevance for ...

These are found in a mature organism. Their function is to replenish all of the types of (differentiated) cells found in that specific tissue. Tissue stem cells are multipotent. This means that ...

These cells regulate key epithelial cell processes such as proliferation, metabolism, apoptosis, senescence and differentiation ... through effects on lung cancer stem cells Upregulation of ...

We investigate how stem cells perceive environmental changes and determine their cell fate, and how niches form and remodel the local environment during lung development, regeneration and disease ...

In the context of lung adenocarcinoma, which is a major form of cancer originating from AT2 cells, understanding how aging affects stem cell behavior is essential for advancing cancer prevention ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

“The idea that you could use electrical fields and 3D mechanical properties to impact stem cells without having to use different kinds of biomolecules or expensive growth factors to drive ...

We identify and characterize gene products affecting stem cell self-renewal, differentiation, proliferation, or survival through the use of CRISPR-Cas9 and RNAi technologies. For our cancer studies we ...

When cells express specific genes that characterise a certain type of cell we say that a cell has become differentiated ... unspecialised cells are called stem cells.