Comments by Michael Karin, Department of Pharmacology, Program in Biomedical Sciences, School of Medicine, University of California, San Diego SIGNAL DISSECTION: Michael Karin and colleagues picked ...

multistep conduit for signal transduction in the cell cycle. You have full access to this article via your institution. The apparently simple step of inhibition of a protein-protein interaction by ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by ...

These intermolecular contacts form complex biological networks, and understanding these networks is a pivotal step towards elucidating the diverse biological actions of signal transduction processes.

The researchers' next step is gaining insight into the structural consequences of linker mutations, which may answer outstanding questions about what limits signal transduction. In the meantime ...

examined what happens after IL-3 binds to its receptor. "I wanted to find out what the next step in the signal-transduction cascade was," she states. "How does receptor activation lead eventually to ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by ...