The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens ...

TFEB and TFE3 are found throughout the animal kingdom, suggesting that the STING-induced autophagy-lysosome pathway is ...

Most importantly, STACT can be dosed systemically, whereas other stimulatory therapies, such as STING agonists, oncolytic viruses, mRNA-delivered cytokines, and toll-like receptor agonists ...