The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens ...
It is not yet understood whether ISCs also express other TLR components and whether the TLR pathway is functionally active in ISCs. Intestinal stem cell-specific TLR4 expression affects the ...
It also describes how TLR signaling could affect the stem cell regulatory pathways. 3 Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center ...