Dopamine neurons in the substantia nigra and the ventral tegmental area are believed to be involved in reward-dependent behaviors. Consistent with this role, they are activated by rewards ...

It receives inputs from the limbic system and the basal ganglia and sends outputs to midbrain areas that are involved in the release of dopamine (the substantia nigra pars compacta and ventral ...

The main neuropathological feature of Parkinson's disease is the loss of dopaminergic neurons in the substantia nigra ... in the dorsal tier and ventral tegmental area demonstrate a much lower ...