Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its ...

Dr. Roddy O'Connor explores "hit & run" serial killing in CAR T cells, discussing how metabolic reprogramming influences ...

IL-10 is dispensable for their suppressive function. Vaccination in glioblastomas does lead to the emergence of tumour-antigen-specific T cells but T cell dysfunction, poor tumour infiltration and ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Researchers have identified a rare type of immune cells that hold the key to maintaining long-term immune responses.

Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune ...

Immune cells called regulatory T cells have long been known for their role in countering inflammation. In the setting of ...

The researchers have identified a rare type of immune cell, called stem-like T cells, that holds the key to maintaining ...

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

Researchers have developed a groundbreaking AI model that identifies tumor-fighting immune cells, enhancing cancer ...

“These epigenetic differences allow us to identify genes that can be manipulated to enhance function,” added lead author Kole DeGolier, PhD. The findings could guide more precise CAR-T cell ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...