The human immune system is a complex network of cells and signals that guards against disease, yet in the case of cancer, it often struggles to mount an effective response. Recent research, published ...

Ovarian tumors are infiltrated by both effector (CD4+CD25-) T cells and by an excess of TREG cells (CD4+CD25+). These TREG cells impede the function of the effectors in combating the tumor.

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent ...

Previous studies on regulatory T-cell (Treg) reconstitution after allogeneic hematopoietic SCT (HSCT) have suggested that, within the GVHD process, imbalance between effector T cells and Tregs may ...

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and likely outcome of HIV infection. While they are no longer used to determine when HIV therapy should be ...

The company recently presented non-human primate data demonstrating that its ctLNPs work by targeting T cells through a target receptor of interest with a strong selectivity for CD8+ and CD4+ effector ...