Mustang’s lead CAR T cell program, MB-106, is a third-generation CAR T cell therapy with a fully human target-binding domain for the treatment of NHL and CLL. MB-106 targets CD20, a clinically ...

TRIM28 is known to recruit chromatin modifiers to its target regions to co-regulate gene expression in multiple cell types. Here authors show that in CD8 + T cells, TRIM28 is an integrant part ...

Interpreting nature's blueprints Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a ...

Drexel's Master of Science in Biomedicine and Cell and Gene Therapy program offers a unique graduate-level opportunity for students at the intersection of medicine and bioengineering. An ever-evolving ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a molecule called messenger RNA.

So I didn’t really have a choice.” In coming months, Wedam’s cells will be shipped to a lab in Tennessee, where technicians will use a gene-editing tool called CRISPR to modify a gene in the ...

Small proteins called histones are tasked with tightly packaging all of that DNA into every cell, like a librarian shoving books into a full bookcase. Histones also play key roles in gene regulation.