Patients with rheumatoid arthritis are associated with an increased risk for heart failure, particularly heart failure with preserved ejection fraction.

CD23 + CD21 hi B cells were found to be involved in arthritis progression in TNF-transgenic mice from the earliest stages of the disease A study exploring the pathogenesis of rheumatoid arthritis ...

However, DcR3 might also contribute to the pathogenesis of RA by downregulating the apoptotic pathways of inflammatory cells, which are mediated by Fas ligand. In fact, defective clearance of ...

RA, an autoimmune disorder affecting 1-2% of ... factor- (TNF- ) and interleukin-1 (IL-1), play a critical role in the pathogenesis of this disorder. IL-1-receptor antagonist (IL-1Ra) is produced ...

Recent research explores how gut microbiome imbalances contribute to rheumatoid arthritis, and how dietary interventions could be key to reducing inflammation and improving patient outcomes.