Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below ... of acute attacks and tophi – which may be considered as the cure ...

These can include: Xanthine oxidase inhibitors (decreases the production of urate ... left untreated. Uric acid crystals can ...

Background A 56-year-old white woman was referred to our institution with a 16-month history of severe, gouty ... birefringent monosodium urate (MSU) crystals by COMPENSATED POLARIZED-LIGHT ...

Insight into the immunopathogenesis of crystal-induced ... in the management of gout attacks, or whether they can prevent such attacks if administered when urate-lowering drugs are initiated.

Gout develops from hyperuricemia—high urate levels in the body ... can lead to permanent joint damage and tophi—painful bumps ...

Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. Despite advancements in management, the incidence and ...

Perspective from David A. McLain, MD, MACR, FACP, FRCP Colchicine for gout flare prophylaxis reduces the risk for cardiovascular events among patients initiating urate-lowering therapy ...

These crystals lead to arthritis and inflammation. A rare, severe, and chronic form of gout that is difficult to treat is called refractory gout. Chronic arthritis, redness tophi (lumps that develop ...