Monosodium urate crystals dissolve and are eliminated from joints and soft tissues as serum uric acid levels drop below ... of acute attacks and tophi – which may be considered as the cure ...

These can include: Xanthine oxidase inhibitors (decreases the production of urate ... left untreated. Uric acid crystals can ...

Insight into the immunopathogenesis of crystal-induced ... in the management of gout attacks, or whether they can prevent such attacks if administered when urate-lowering drugs are initiated.

Background A 56-year-old white woman was referred to our institution with a 16-month history of severe, gouty ... birefringent monosodium urate (MSU) crystals by COMPENSATED POLARIZED-LIGHT ...

If gout itself contributes an additional cardiovascular risk, is this effect explained by the inflammatory state caused by the deposition of monosodium urate crystals? During an acute attack of ...

Gout develops from hyperuricemia—high urate levels in the body ... can lead to permanent joint damage and tophi—painful bumps ...

Among patients with gout in the US, Black individuals and those living in the South were associated with reduced adherence to allopurinol.

Perspective from David A. McLain, MD, MACR, FACP, FRCP Colchicine for gout flare prophylaxis reduces the risk for cardiovascular events among patients initiating urate-lowering therapy ...

Uric acid-induced kidney damage can occur through various mechanisms, including the activation of pro-inflammatory pathways and the accumulation of urate crystals in the kidney tubules ...

Gout is a condition when urate, a substance in the body, builds up and forms needle-shaped crystals in your joints. This leads to pain, swelling, redness, and changes in the movement and use of ...

These crystals lead to arthritis and inflammation. A rare, severe, and chronic form of gout that is difficult to treat is called refractory gout. Chronic arthritis, redness tophi (lumps that ... not ...