other IDL particles are hydrolyzed in the liver by hepatic-triglyceride lipase to form LDL, a smaller, denser particle than IDL. LDL is the main carrier of circulating cholesterol within the body ...

DHAP, a marker of triglyceride synthesis, was significantly associated with fibrosis. Independently, ALT—a nonspecific marker of liver inflammation—was equally associated. DHAP and ALT ...

reduced liver fat and inflammation and decreased fibrotic remodeling. These effects were achieved by interfering with the PPARα signaling pathway and promoting the synthesis of hydrophilic bile ...

increased postprandial CHYL and increased VLDL particles may increase free FA delivery to the liver, and increase hepatic lipid content, which are substrates for TG synthesis and, thus ...

Thus, during the fed state the liver responds directly to blood glucose ... such as glycogen and lipid synthesis by hepatocytes. The whole picture becomes far more complex when we consider how ...

There were no effects on triglyceride or ... was not changed but bile-acid synthesis appeared to be stimulated, suggesting that KB2115 may act to induce net liver cholesterol removal.

On a normal chow diet, the mice over accumulate cholesterol and fats in the liver, but levels of SREBP's and other SREBP target genes (molecules that sense cholesterol and regulate its synthesis ...