Background: Trisomy 18 is the second most common autosomal trisomy in liveborn infants, characterised by severe psychomotor and growth retardation. The median survival is 19 days, with only 5-8% ...

Symptoms of Dandy-Walker vary with age and can include the following ... Dandy-Walker syndrome has been found to occur most often in children who have an extra copy of chromosome 18 (trisomy 18).

Among 19 autopsied cases of 17–18 trisomy syndrome, 10 confirmed by cytogenetic studies, nine diagnosed on the basis of phenotypic characteristics, seven cases of neonatal hepatitis were found ...