Tuberous Sclerosis Complex (TSC): A genetic disorder characterized by the growth of benign tumors in multiple organs. mTOR (mammalian target of rapamycin): A protein that regulates cell growth ...

The opposite effect was observed in cells that were deficient for the tuberous sclerosis complex (TSC; an endogenous negative regulator of mTOR activity), in which mTOR is hyperactive: Tsc2 − ...

These skin findings, together with pulmonary lymphangioleiomyomatosis, pointed to the diagnosis of tuberous sclerosis complex (TSC). TSC is a genetic disorder characterized by the presence of ...

Johnson, who earned over $300 million when his mobile and web payment company Braintree was acquired by PayPal in 2013, has ...