Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.
To confirm that protein transfer isn’t limited to cultured cells, the team injected cancer cells into a ... The findings suggest that transfer of THY1 from CAF to endothelial cells helps immune cells ...
CAR T cell therapy revolutionizes oncology by using engineered T cells to target and eliminate cancer cells, improving outcomes in hematological malignancies.
By successfully turning the “cold” tumor into “hot” – transforming the tumor microenvironment from having low immune activity to an active immune environment – ERNA-101 may not only lead to improved ...
For the first time, researchers have used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time.
ERNA-101 cells were detected in the tumor after 42 days. Relative to the control groups, the ERNA-101 group exhibited substantially higher T cell infiltration and reduced tumor size. Additionally ...