This treatment method has shown effectiveness in various cancers, including melanoma and lung cancer, but some cancers have ...

Diffuse midline gliomas (DMGs) are some of the most aggressive and deadly childhood brain tumors. These cancers, which mainly ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

Emerging strategies, such as logic-gated and dual-targeting CAR-T cells, offer practical solutions to overcome these hurdles. Furthermore, we explore the combination of CAR-T cell therapy with immune ...

About PYX-201 PYX-201, an antibody-drug conjugate (ADC) with a microtubule inhibitor (optimized auristatin) payload that uniquely targets Extradomain-B Fibronectin (EDB+FN), a non-cellular structural ...

ERNA-101 cells were detected in the tumor after 42 days. Relative to the control groups, the ERNA-101 group exhibited substantially higher T cell infiltration and reduced tumor size. Additionally ...

This successful proof-of-concept study demonstrated massive T cell infiltration after ... researchers developed an ovarian tumor model by injecting ID8 cells intraperitoneally into mice.

By successfully turning the “cold” tumor into “hot” – transforming the tumor microenvironment from having low immune activity to an active immune environment – ERNA-101 may not only lead to improved ...