Limited to estrogen receptor-positive breast cancer (ER+) the compound addresses many common concerns with existing treatment ...

the therapy is typically initiated in mice harboring a small tumor volume, which does not reflect the large tumor burden observed in most individuals with metastatic disease. Figure 1: Comparing a ...

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late effects ...

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women.

Homozygous mice with a high number of mutations had the opposite effect, blocking tumor growth. "Until now, researchers have been focusing on an all-or-nothing approach, thinking that a lot of ...

Introducing the M@P nanoplatform: a novel approach to cancer therapy that triggers pyroptosis and ferroptosis, boosting ...

Having previously reported the preclinical efficacy and safety of this novel cell-penetrating mini-protein in mouse models ... for the treatment of several tumor types. OMO-103 has since gained ...