An enzyme called MICAL2 promotes tumor growth and ... disease to an advanced stage. MICAL2 appears to supercharge the KRAS signaling pathway, which regulates cell growth, proliferation, and ...

regulating their growth and aggressiveness. Importantly, they observed that HNF4A was significantly shut down in the very early stages of the cancer, declining further as the disease spread.

(B) Entosis in xenograft tumor, loser cell labeled with GFP ... We have shown that entosis occurs in cancers, and that this process inhibits transformed growth, suggesting that entosis can act as a ...

--(BUSINESS WIRE)--Circle Pharma, a clinical-stage biopharmaceutical ... elicits anti-tumor activity in breast cancer patient-derived xenograft models Poster Number: P2-05-29 Date and Time ...