The question now was, how widespread is this, and is this happening in all cancer types? This is how I got interested in alternative cleavage and polyadenylation. At the end of every mRNA there is a ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

Individual genes express multiple mRNAs by pre-mRNA alternative splicing, alternative polyadenylation or use of alternative promoters (first exons). As a result, individual genes express multiple ...

Dr. Imada says his project may be the first in-depth, genome-wide exploration of alternative polyadenylation's role in prostate cancer. He and his team will use computational analysis of RNA ...