Mass spectrometry has become the standard tool to map sites of ubiquitination, which is a covalent protein modification with a central role in regulating cellular processes 1. Ubiquitin is a small ...

The Bhogaraju Group at EMBL Grenoble has devised a novel approach to investigating ubiquitination, a crucial process of ...

Covalent modification of the oncogene product Mdm2 by the ubiquitin-related protein SUMO1 protects it from ubiquitination and enhances its E3 ligase activity towards p53 in vitro. Disappearance of ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites. Viruses often ...