Dysfunctional endothelium displays activation of vascular NADPH oxidase, uncoupling of endothelial nitric oxide synthase, increased expression of endothelin 1, a changed balance between the ...
研究人员从GEO公共数据库中选择了具有动脉粥样硬化保护效果的干预(他汀类药物或层流剪切应力)测序数据集,以及动脉粥样硬化患者斑块的基因表达数据集,发现胰岛素样生长因子结合蛋白6(IGFBP6)可能是一种潜在的血管稳态相关分子。已有研究表明,IGFBP ...
Research reveals IGFBP6's role in suppressing vascular inflammation and atherosclerosis, suggesting it as a novel target for ...
In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...
The three cell types that Khalil's approach generated were endothelial cells (the vascular cells that form the lining of blood vessels) and smooth muscle cells and pericytes (perivascular cells ...
A groundbreaking review highlights significant advancements in the understanding and treatment of cerebral vascular ...
Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...