Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...

The pair had helped identify a still-unnamed disease, which they had tied to a particular gene and to a particular somatic mutation—a genetic change that had not been passed down from a parent and was ...

A nonsense mutation is a genetic mutation in a DNA sequence that results in a shorter, unfinished protein product. DNA is a chain of many smaller molecules called nucleotides. During protein ...

DNA contains genes that carry instructions for the manufacture of a protein. If a mutation occurs in a gene that results in a change to the sequence of DNA bases, then the structure of the protein ...

The gene mutation was isolated in a family in northern Italy where under half of the relations developed the disease. View on ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...