Even within these fields, researchers would often define themselves as integrin researchers, cadherin experts or epidermal growth factor receptor (EGFR) signalling specialists. Over the last 20 ...
Several targets almost fulfill this requisite: tenascin-C, podoplanin/aggrus, EGF receptor (EGFR), EGFRvIII ... extradomain B of fibronectin, integrin α v β 3, histone H1 complexed to ...
Integrins are very attractive therapeutic targets in oncology. The anti-tumor mechanisms of integrin-targeting drugs have been validated both in vitroand in vivo. Integrin-targeting drugs are ...