Another scenario would have been that the mRNA poly(A) tail was fully synthesized prior to nuclear export and was shortened in the cytoplasm. This was actually confirmed in later experiments.
tail at the 3′ end of the mRNA. In addition, we do not yet understand the precise signalling pathways that coordinate histone synthesis in the cytoplasm and DNA replication in the nucleus ...
Get Instant Summarized Text (Gist) A mechanism regulating mRNA poly(A) tail length in early embryos has been identified, involving the protein MARTRE1, which inhibits the CCR4-NOT complex. MARTRE1 ...
The commercially available mRNA has been enhanced with a 5’ cap and polyA tails and is prepared for use in any research project. Spend less time and effort creating and generating mRNA.