Lipids formulated with a bioreducible linker form the wall of nanoparticles encapsulating the mRNA of Cas9 plus sgRNA. Upon entering the cell, in vitro or in vivo, the linkers are broken and the ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

LUTHOR HD 3’mRNA-seq libraries display comprehensive ... Gene and transcript detection rates including Venn-style diagrams for cell pairs at representative read depth of 20k and 1M raw reads ...