See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

RNAi therapeutics are inspired by a mechanism that exists in all cells to regulate gene expression, using specially-designed small interfering RNA (siRNA) that is complementary to specific human ...

WVE-007 is an investigational GalNAc-conjugated small interfering RNA (siRNA) designed to silence Inhibin βE (INHBE) gene ...

altered gene expression and stimulation of immunogenic responses. Nanotoxicity is particularly an issue in siRNA nanocarrier development due to their polycationic charges, complex design and ...

The ability to control gene expression has always been indispensable in order to elucidate the function ... The small molecules used to control the RNA switch can be any cellular biomolecule, ...

Ractigen Therapeutics is dedicated to advancing its pipeline, including RAG-17 and RAG-21, while exploring innovative treatments for rare diseases. Through its groundbreaking work in RNA-based drug ...

RXI-231 significantly reduced tyrosinase mRNA expression, and correspondingly reduced in melanin content in both normal ... (NASDAQ: PHIO) is a clinical-stage biotechnology company advancing its ...

Ractigen Therapeutics begins patient dosing in phase I trial of RAG-17 in SOD1-ALS: Nantong, China Friday, December 27, 2024, 12:00 Hrs [IST] Ractigen Therapeutics, a clinical-sta ...