See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

Although these molecules are only 21 to 25 base pairs in length, they also work to inhibit gene expression. Specifically, one strand of a double-stranded siRNA molecule can be incorporated into a ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Their results, published in the Proceedings of the National Academy of Sciences, highlight the role of gene expression in the evolution and function of the human brain. Interpreting nature's ...

Benitec has a market cap of $250mn, $67.8mn in cash, and a cash runway of over 10 quarters, but faces risks due to its small ...

More information: Shireesha Manturthi et al, Nanoparticles Codelivering mRNA and SiRNA for Simultaneous Restoration and Silencing of Gene/Protein Expression In Vitro and In Vivo, ACS Nanoscience ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

The Phase Ib trial is set to test a gene therapy designed to target a rare disorder that causes muscle and respiratory failure.

The US biotech has just reported phase 2 trial results with the small, interfering RNA (siRNA) gene-silencing drug showing that it an cause a 90% or greater reduction in Lp(a) levels – a risk ...

Researchers measure gene expression by observing the amount of mRNA a specific gene produces. As scientists began to understand the role of the genome as life's blueprint, they thought that ...