The work on secreted miRNA has led to extracellular vesicle-based delivery of small interfering RNA (siRNA) therapy. This white paper describes research undertaken by groups at SLiS of NJU ...

et al., Patel, D. J. & Hung, M. C. (2013). EGFR modulates miRNA maturation in response to hypoxia through phosphorylation of Ago2. Nature 497, 383-387. Viral Suppressors. Viruses have organized a ...

Argonaute proteins also contribute to the maintenance of chromosome integrity, are involved in siRNA and miRNA maturation and can even participate in the production of a new class of small non ...

You can gain deeper understanding of expression patterns of small non-coding RNAs by using assays that retain spatial organization at single cell resolution. Traditional methods such as NGS, can ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

Various gene silencing technologies like siRNA, miRNA, ribozymes, DNAzymes have shown promise as therapeutics agents against viral diseases. RNAi-based drugs against viruses such as ebola virus ...

View Full Profile. Learn about our Editorial Policies. The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi ...