4 What pathophysiological mechanisms can explain these epidemiological observations? If gout itself contributes an additional cardiovascular risk, is this effect explained by the inflammatory ...

Counterargument: Combine Therapies With Different Mechanisms of Action In his counterargument, Pérez-Ruiz contended that gout is not in fact a metabolic disease and suggested that combining ...

Gout is a form of inflammatory arthritis that causes severe pain and swelling in one or more of your joints. These attacks happen suddenly when there's a buildup of uric acid, a chemical found ...

Gout occurs when your body is not able to excrete ... The authors state that these drugs cause high uric acid through a few different mechanisms. In general, however, they affect uric acid ...

The previous paragraphs described certain gout scenarios where a faster crystal clearance may be beneficial. As shown, time to achieve crystal dissolution will heavily depend on the SUA level reached.

Researchers have found that reduced pulmonary function strongly increases the risk of developing gout. Pulmonary function is ...