4 What pathophysiological mechanisms can explain these epidemiological observations? If gout itself contributes an additional cardiovascular risk, is this effect explained by the inflammatory ...

A recent study by researchers from the University of California San Diego and collaborators has uncovered a new molecular ...

auckland.ac.nz Objective: The underlying basis of bone erosion in gout remains speculative. The aim of this study was to understand the mechanisms of bone erosion in gout using non-invasive imaging ...

Gout is one of the most severe and frequent rheumatic diseases. Clinical manifestations of gout arise from uric acid crystal deposition in the musculoskeletal tissue. At high concentrations of uric ...

A similar association was seen between incidence of gout and intake of vitamin C from ... Choi and colleagues note a number of potential mechanisms by which vitamin C increases the excretion ...

Objectives Gout, as the most prevalent form of inflammatory arthritis, necessitates the use of animal models to investigate the molecular mechanisms involved in its development. Therefore, our ...

The previous paragraphs described certain gout scenarios where a faster crystal clearance may be beneficial. As shown, time to achieve crystal dissolution will heavily depend on the SUA level reached.

While gout and diabetes are distinct medical conditions with different underlying mechanisms, they can coexist in people who have multiple risk factors, such as obesity, and insulin resistance.

Conclusions The anti-inflammatory effect of Chinese herbal extracts (TGP and SIN) on the multiple targets of the inflammatory model may be one of its mechanisms of action for the prevention and ...

Gout occurs when your body is not able to excrete ... The authors state that these drugs cause high uric acid through a few different mechanisms. In general, however, they affect uric acid ...

Gout is an inflammatory type of arthritis that’s caused by crystal deposits that build up in joint. It can be confused for another condition that involves crystal build up. Learn how to recognize the ...