面对今年这波流感疫情，我们有一个非常直观的感觉就是流感病毒在引起肺炎的同时非常容易合并有真菌感染，尤其是曲霉菌的感染，在重症监护病房的这种病人表现更为明显。有研究发现，ICU患者中IAPA发生率高达19%，病死率超过50% 1，那么为什么会出现这种情况呢？

Aspergillosis is an infection caused by Aspergillus, a fungus naturally present in the environment. Most people come into ...

G-CSF, GM-CSF, IFN-γ, TNF-α and IL-12 have been shown to enhance antifungal activity of human phagocytes and exert a protective effect in animal models of invasive aspergillosis. A protective ...

F2G, a University of Manchester spinout company, is to partner a major Japanese pharmaceutical company in the commercialisation of a novel antifungal treatment it developed for invasive aspergillosis ...

Invasive aspergillosis is a serious life-threatening condition in immunocompromised patients that requires urgent treatment. Patients are often prescribed antifungal drugs before a diagnosis is ...

Background Voriconazole is approved for treatment of invasive aspergillosis and other invasive fungal infections, but the role for therapeutic drug monitoring (TDM) is not clear. Methods We ...

The Manchester-based company said the new cash will help it to complete the late-stage development of olorofim, a novel oral antifungal for invasive aspergillosis and other serious fungal ...

Emily said: “COPD is the most widespread non-infectious disease of the lungs. It is progressive and irreversible. Advanced COPD often leads to hospitalisation and sometimes invasive aspergillosis (IA) ...