A multi-omics study reveals that impaired branched-chain amino acid (BCAA) catabolism is a key driver of sarcopenia, ...

This leads to a massive energy deficiency from which the cell cannot escape by switching to other metabolic pathways, and ultimately to slowed tumor growth in mice. Glycolysis is a central ...

Most mutations that decreased antibiotic susceptibility were related to specific metabolic pathways. A MIC-increase to ...

There are two key pathways of glucose metabolism: glycolysis and oxidation. Glycolysis can be considered akin to chopping down a tree and cutting it into several large pieces, whereas oxidation ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon ...

This corresponded with increased glycolysis early in infection and then decreased glycolysis after 24 hours, paralleling the greater intracellular oxidation, suggesting that the parasite alters ...

Cancer cells are capable of rapidly adapting their metabolism to thrive in challenging environments. This metabolic reprogramming provides the energy needed for tumor growth and is a key area for ...

Download this Application Note to see how PHCbi applied LiCellMo to THP-1 and NB-4 cells to continuously measure changes in cell metabolism when in the presence of a glycolysis inhibitor and a ...