When rotated, a hole formed in their center, resulting in a tubelike structure. Upon transplanting the organoid into mice, it reportedly grew to the same size as a mouse's small intestine.
Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation—and relocation—as they fight infections in the small intestine.
Because sex and pregnancy hormones regulate RANK–RANKL signalling, we assessed the structure ... exposed mouse and human intestinal organoids (self-organized 3D tissues derived from intestine ...