PSCs pack themselves into clusters called spheroids, where they encounter microenvironments like those they experience in the body. "Pluripotent stem cells like to be in contact with each other ...

More information: Hideki Kobayashi et al, Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell–Derived Cardiac Spheroids, Circulation (2024). DOI: 10.1161 ...

I n a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs ...

Organoids are self-organizing, three-dimensional structures derived from adult or induced pluripotent stem cells. They provide a unique physiologically relevant ... maintenance and characterization of ...

Consisting of clusters of purified heart muscle cells (cardiomyocyte spheroids) derived from induced pluripotent stem cells (iPSCs), designed to restore heart muscle and function, the clinical ...

3D cell culture for spheroids involves cultivating cells in a three-dimensional environment, allowing them to naturally form spherical clusters that closely mimic the structure and function of ...

The cells were produced from generic human stem cells that could be turned into ... heart muscle cells into microscopic three-dimensional spheroids that mimicked the structure and function of ...