In the new study, which focused on breast cancer, the authors report that tumor-associated macrophages (TAMs), a type of immune cell found abundantly in the tumor microenvironment, respond to the ...

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

The study introduces an innovative tracer targeting CD163, a molecular receptor on tumor-associated macrophages—immune cells that support tumor growth and protection. The tracer is based on ...

activating nearby antigen presenting cells (APCs), notably dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct phagocytosis of ...

Discover how immune iFRET biomarkers offer new insights into predicting response to neoadjuvant melanoma therapy, driving advances in precision immunotherapy.

How would you summarize your study for a lay audience?Ependymoma (EPN) is a common form of brain cancer in children, with few ...

and tumor-associated macrophages as well as uncovering crucial adaptive T cell regulation pathways in cancer. Using murine genetic cancer models and patient tumor specimens, we were the first to ...

The Arkansas Integrative Metabolic Research Center will host Jeffrey Rathmell, a professor of pathology, microbiology and immunology from Vanderbilt University on Wednesday, Jan. 22.

A research team has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone interferon-I combined with local application of Imiquimod.

The LifeTracDx tests were made possible by Creatv’s discovery of cancer-associated macrophages in cancer patient blood and their clinical applications. These macrophages are scavenger cells that ...