This is particularly true of the immune system. Autoimmune diseases show a clear predominance in women, implying a central role for estrogen in their development. A thorough elucidation of that ...

Autoimmune disease is controlled by host genes and the environment. Both can increase susceptibility to autoimmunity by affecting the overall reactivity and quality of the cells of the immune system.

The 2024 American College of Rheumatology (ACR) annual meeting spotlighted transformative advancements in cell therapies for autoimmune diseases, with chimeric antigen receptor (CAR)-T therapies ...

The research & development (R&D) of novel therapeutic agents for the treatment of autoimmune diseases is challenged by ... to correctly reflect the lack of response in MMPs under IL-10 overexpression, ...

According to the Arthritis Foundation, about 1 to 3 percent of people who take methotrexate and 10 percent ... Managing an autoimmune disease can be a handful. Dealing with hair loss on top ...

If you live with a chronic or autoimmune disease, you may be wondering if it is wise to get a tattoo. Whether or not it is safe to get a tattoo is a discussion that is best had with a healthcare ...

Most B cells produced in the bone marrow have some level of autoreactivity. Despite efforts of central tolerance to eliminate these cells, many escape to periphery, where in healthy individuals, they ...

More information: Xiang Xiao et al, Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease models, Journal of Clinical Investigation (2024). DOI: 10.1172/JCI183671 ...

Autoimmune disorders occur when immune cells go wrong and attack the body’s own tissues. Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, ...

Is IBD an autoimmune disease? While it has similarities with autoimmune diseases, IBD is a little different. IBD falls under the umbrella of immune-mediated inflammatory diseases (IMIDs).

Autoimmune diseases are a pathophysiological state wherein immune responses are directed against, and damage, the body's own tissues (autoimmunity). Common examples of autoimmune disease include ...