On a population level, the effects of PPI are more prominent than the effects of antibiotics or other commonly used drugs. Proton pump inhibitors (PPI) use is associated with increased risk of enteric ...

The abuse of antibiotics has accelerated the emergence of drug-resistant bacteria ... The mechanisms underlying the antibacterial activity of prodigiosin include the disruption of the cell membrane ...

Objectives This study aimed to assess whether the combined use of proton pump inhibitors (PPIs) with non-steroidal anti-inflammatory drugs (NSAIDs) or antibiotics (penicillins ... 2.40 to 6.52), 2.57 ...

In this week’s episode of "The Top Line," we bring you a special conversation from earlier this month at our New York City gala, where we celebrated this year’s Fierce 50 honorees. On stage ...

FUTURE PROJECTIONS By 2030, global antibiotic use is expected to rise by over 50%, reaching 75.1 billion daily doses. This dramatic growth underscores the urgent need for action to promote more ...

Different pro-inflammatory stimuli elicit varying effects on bioenergetic parameters, and pharmacologic and genetic models of electron transport chain inhibition show no causative link between ...

On 15 January, the two agencies released respective lists of medicines approved last year. The FDA approved 50 novel drugs ...

Table 1. Comparison of the specific enzymatic activity of the SPases for different synthetic peptides and a preprotein substrate (topmost). †Amino acids are abbreviated as single letter codes ...