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辐射对药物转运体以及药物代谢动力学的影响
鉴于辐射能够引起机体一系列生理甚至病理变化,尤其是会造成药物转运体的蛋白或功能改变,所以辐射可能对药物在机体内的吸收、分布、代谢与排泄过程产生一定影响。关于辐射对药物代谢动力学影响的研究最早可追溯到20世纪80年代,该研究对高原人群、放疗患者以及其他 ...
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